An Olivier Giroud goal was the difference in the first meeting and now Chelsea are favourites to progress to the quarter-finals with the second leg at Stamford Bridge.
Diego Simeone’s side will not make it easy, though, with Atletico still top of La Liga, four points clear of Barcelona and seven ahead of Real Madrid.
When is Chelsea vs Atletico Madrid?
The match kicks off at 8pm on Wednesday 17 March at Stamford Bridge.
What TV channel is Chelsea vs Atletico Madrid on and is there a live stream?
BT Sport 2 will be showing the game live with coverage starting at 7pm. Subscribers can stream the action on BT Sport Player or on the BT Sport app.
Chelsea are without suspended duo Jorginho and Mason Mount, while Thiago Silva and Tammy Abraham are out injured.
Mount and Jorginho are the joint top-scorers under the Tuchel reign with three goals each.
Chelsea vs Atletico Madrid odds
12/5 Atletico Madrid
Odds courtesy of Betfair
Chelsea vs Atletico Madrid head-to-head in last five meetings
23 Feb 2021: Atletico Madrid 0-1 Chelsea – Champions League
05 Dec 2017: Chelsea 1-1 Atletico Madrid – Champions League
27 Sep 2017: Atletico Madrid 1-2 Chelsea – Champions League
30 Apr 2014: Chelsea 1-3 Atletico Madrid – Champions League
22 Apr 2014: Atletico Madrid 0-0 Chelsea – Champions League