The Blues have spent heavily during the close season, making significant and eye-catching additions to a squad which finished third last term and reached the final of the FA Cup.
Lampard has added to his forward line with signing of Timo Werner, while the Kai Havertz transfer saga came to a satisfactory conclusion from a Chelsea perspective last Friday.
Hakim Ziyech, however, will miss the trip to the south coast with the knee injury he picked up in a pre-season friendly draw against Brighton 10 days ago.
Fellow new recruit Ben Chilwell, a £50million signing from Leicester, is also nursing a knee injury, while the experienced Thiago Silva, who joined on a free from PSG, will only take part in his first training session with his new team-mates this weekend.
‘Hakim Ziyech took an injury to his knee against Brighton and he he won’t be fit, hopefully it’s a matter of weeks, we have to see,’ confirmed Lampard at his pre-match press conference.
‘Chilwell is working towards fitness but he won’t be fit. He’s developed and improved so it’s good news.
‘Thiago is now in London but he’s not training with us until the weekend so I doubt he will be in contention for Brighton. Out of the new ones that’s where we’re at.’
He added: ‘I understand that (people see Chelsea as challengers) and I hope Chelsea fans are excited because we have brought in high level of players.
‘But I know what it takes to win the Premier League. City and Liverpool have run over a few years. I hope we will improve. We know expectations are there, but we want to improve and not get ahead of ourselves.’