United might be in changeable form in the Premier League but they have started their European campaign wonderfully, beating Paris Saint-Germain 2-1 away and then thrashing RB Leipzig 5-0 at home last week.
They now go to Istanbul to try and maintain their lead at the top of Group H and put them very close to a place in the knockout stages after just three games.
The Turkish side have lost both their first two matches without scoring a goal and have not been in good form domestically, sitting seventh in the Super Lig with 10 points from their first seven games.
What time is Istanbul Basaksehir vs Man Utd?
The match kicks-off at 5.55pm on Wednesday 4 November at the Başakşehir Fatih Terim Stadyumu.
What TV channel is Istanbul Basaksehir vs Man Utd on and is there a live stream?
BT Sport 3 will be showing the game live with coverage starting at 5.15pm.
Subscribers can stream the action on BT Sport Player or the BT Sport app.
Manchester United are still without Eric Bailly, Jesse Lingard, Phil Jones and summer signing Alex Telles for this contest.
Edinson Cavani could feature for the Red Devils as he still looks for his first goal for his new club.
Istanbul Basaksehir vs Man Utd odds
2/5 Man Utd
Odds courtesy of Betfair