Salah was clearly unhappy with the call as television cameras caught the Egypt international repeatedly shaking his head on the Liverpool bench.
And Salah’s representative, Ramy Abbas Issa, also showed his displeasure towards Klopp’s decision as he posted a full stop on Twitter just minutes after the forward was brought off.
However, Liverpool supporters quickly slammed Salah’s agent for his reaction to the substitution.
One Liverpool fans replied: ‘You know your player isn’t bigger than this club, right? He didn’t make LFC the legendary club that it is, right? And this attitude is unprofessional and absolute bulls***, yeah???’
Another Liverpool supporter replied: ‘You’re his agent and you’re literally making things worse for your own client, hope the little bit of attention is worth it.’
A third Liverpool fan wrote: ‘This is what happens when agents get paid too much money for transfers, they get loud and push agendas.’
Salah has already shown his displeasure towards Klopp earlier this season when he was substituted in the 1-1 draw with Brighton in November.
When asked if he encourages Klopp to rotate his attackers during an interview with beIN Sports in January, Salah said: ‘This is a very difficult question for me to answer.
‘But I cannot discuss this because it has to do with the tactics and viewpoint of the coach.
‘But if you are asking me about my opinion, I like to play in every match, the full 90 minutes, and even 95 minutes.
‘I want to play until the last second of the game.
‘But at the end of the day, the coach decides, and the players respect his decision.’