United have recovered admirably from their 6-1 defeat against Tottenham prior to the international break, recording impressive back-to-back victories against Newcastle and PSG amid something of a defensive injury crisis.
Skipper Harry Maguire missed the midweek win in the French capital, while Mason Greenwood has been omitted from the last two matchday squads.
Experienced deadline day signing Edinson Cavani, meanwhile, has been forced to wait to make his debut having been forced to quarantine following his arrival earlier this month but he could be in contention to feature against Frank Lampard’s side at Old Trafford.
Speaking at his pre-match press conference, Solskjaer said: ‘I hope and expect all three of them to be available for selection.
‘Of course we’ve got a training session this morning which is the last chance of preparation, but they’ve all got a chance, all of them.
‘Edinson needs to tick all the boxes that he’s gone through in his programme to be ready and make an impact. I’ll have a discussion with him today, as well as with Mason and Harry.’
Tomorrow’s opponents Chelsea have endured a mediocre start to the new campaign, despite a near unprecedented summer of spending. Lampard’s side have won just two of their opening five Premier League fixtures and were held to a stalemate by Sevilla at Stamford Bridge in midweek.
He added: ‘[Chelsea’s start] is like many of us, some very good games, some lesser performances, football is just settling now and teams are just getting into their shape.
‘We know it’s gonna be a tough game against Chelsea, we had maybe four or five games against them last year, two teams that know each other really well.’