Former Real Madrid midfielder Isco Alarcon provided an assist and scored the winner against his former side to give Real Betis a famous win.
Consequently, Atletico Madrid took advantage of the shock loss to assume pole position in the La Liga race.
Real Madrid fell to a 2-1 loss despite Brahim Diaz’s opener in the 10th minute.
However, Isco provided the assist as Johnny Cardoso equalized for the home side in the 34th minute.
Isco went ahead to convert a seemingly controversial penalty ten minutes into the second half to give Real Betis the lead and the eventual winner.
Diego Simeone’s men, faced with a daunting task against Copa Del Rey reigning champions Athletico Bilbao, showed character as they earned a narrow win.
Former Manchester City striker Julian Alvarez scored six minutes after the hour mark to give the Rojiblancos the needed victory.
The Argentine crowned Marcos Llorente’s individual briliance with a fine strike into the bottom right corner.
Atleti’s win over Bilbao take them to the top of the log momentarily with 56 points pending the outcome of Barcelona’s clash at home to Real Sociedad on Sunday.
In other results, Girona winless run continues as they played out a two-all draw against Celta Vigo at home. Girona are now winless in their last four matches.
Meanwhile Rayo Vellecano remain winless in theee games a one-all draw ay home fo Sevilla.